KATE KARLSON SOFTWARE
KATE KARLSON TRIAL

In this role, I assisted with adaptation of an actionability protocol from the adult setting to the pediatric setting. PMCID: PMC7785634.įrom 2017-2021, I was a member of the Clinical Genome Resource ( ClinGen ) Actionability Working Group. Participant Reactions to a Literacy-Focused, Web-Based Informed Consent Approach for a Genomic Implementation Study. Kraft SA, Porter KM, Duenas DM, Guerra C, Joseph G, Lee SS, Shipman KJ, Allen J, Eubanks D, Kauffman TL, Lindberg NM, Anderson K, Zepp JM, Gilmore MJ, Mittendorf KF, Shuster E, Muessig KR, Arnold B, Goddard KAB, Wilfond BS. Systemic Barriers to Risk-Reducing Interventions for Hereditary Cancer Syndromes: Implications for Health Care Inequities. Mittendorf KF, Knerr S, Kauffman TL, Lindberg NM, Anderson KP, Feigelson HS, Gilmore MJ, Hunter JE, Joseph G, Kraft SA, Zepp JM, Syngal S, Wilfond BS, Goddard KAB. Adaptation and early implementation of the PREdiction model for gene mutations (PREMM5™) for Lynch syndrome risk assessment in a diverse population. Mittendorf KF, Ukaegbu C, Gilmore MJ, Lindberg NM, Kauffman TL, Eubanks DJ, Shuster E, Allen J, McMullen C, Feigelson HS, Anderson KP, Leo MC, Hunter JE, Sasaki SO, Zepp JM, Syngal S, Wilfond BS, Goddard KAB.

KATE KARLSON TRIAL

Cancer Health Assessments Reaching Many (CHARM): A clinical trial assessing a multimodal cancer genetics services delivery program and its impact on diverse populations. Mittendorf KF, Kauffman TL, Amendola LM, Anderson KP, Biesecker BB, Dorschner MO, Duenas DM, Eubanks DJ, Feigelson HS, Gilmore MJ, Hunter JE, Joseph G, Kraft SA, Lee SSJ, Leo, MC, Liles EG, Lindberg NM, Muessig KR, Okuyama S, Porter KM, Riddle LS, Rolf BA, Rope AF, Zepp JM, Jarvik GP, Wilfond BS, Goddard KAB, CHARM study team. I later received a career development supplement to CHARM to evaluate the effectiveness of our adaptations at improving access to risk assessment in our underserved study population. Additionally, I worked with the development team to design and implement a data model supporting data capture of patient interactions with the web-based risk assessment and consent, and provided analytic support for downstream analyses leveraging this data model.

KATE KARLSON SOFTWARE

I also led the software development team in their implementation of a web-based informed consent for study-provided genomic testing for those participants who screened at risk. I led two multi-site workgroups (one for each tool) and an onsite software development team, as well as collaborated with patient stakeholders in an iterative design process. For CHARM, I led the adaptation of two validated, guideline-recommended risk assessment algorithms (PREMM5™ and B-RST™ 3.0) to patient-facing web applications for implementation in the low-literacy, low-resource study population. CHARM investigates strategies to improve access to genetic counseling and testing for a diverse group of adults with increased risk of hereditary cancer syndromes. įrom 2017-2021, I worked on the Cancer Health Assessments Reaching Many (CHARM) study, a CSER Consortium study funded by the NHGRI with co-funding by NCI. Utilization of electronic health record data to evaluate the association of urban environment on systemic lupus erythematosus symptoms. Song J, Forrest N, Gordon A, Kottyan L, Mittendorf KF, Wei WQ, Ramsey-Goldman R, Walunas T, Kho A.

Returning integrated genomic risk and clinical recommendations: The eMERGE study. Linder JE, Allworth A, Bland ST, Caraballo PJ, Chisholm RL, Clayton EW, Crosslin DR, Dikilitas O, DiVietro A, Esplin ED, Forman S, Freimuth RR, Gordon AS, Green R, Harden MV, Holm IA, Jarvik GP, Karlson EW, Labrecque S, Lennon NJ, Limdi NA, Mittendorf KF, et al. I am also directing the integration of study-generated clinical decision support to the EHR. The eMERGE study is utilizing MeTree™ for family history assessment, and I am overseeing the implementation of MeTree™ as a SMART on FHIR application at our site. This role involves working directly with VUMC HealthIT to integrate study-generated discrete and non-discrete data, including family history and genomic data, directly into the EHR. I currently serve as the EHR Integration site lead for Vanderbilt University Medical Center (VUMC) on the NHGRI-funded Electronic Medical Records & Genomics (eMERGE) Network.

Kate karlson